12:15pm - 1:15pm
Location:聽Lecture Hall 10
罢颈迟濒别:听鈥淗ijacking of Stress Coping Circuits And Addiction Risk and Relapse Outcomes鈥
础产蝉迟谤补肠迟:听How is alcohol and drug use linked to stress? Does drug use hijack the ability to face and cope with stress and drive compulsive seeking? This lecture will discuss neural circuits underlying adaptive stress coping and how drug misuse hijacks that to drive higher craving and drug intake and also result in high rates of relapse and treatment failure. The final part of the lecture will present adrenergic and neurosteroid targets that may reverse such stress-related hijacking of adaptive coping to improve treatment outcomes.
Biography:
Rajita Sinha, Ph.D. is the Foundations Fund Endowed Professor of Psychiatry, and Professor in Neuroscience and in Child Psychiatry at the Yale University School of Medicine. She is a
licensed Clinical Psychologist and Clinical Neuroscientist, Chief of the Psychology Section in Psychiatry and Deputy Chair of Psychiatry for Psychology at the Yale University School of
Medicine. She is the founding director of the Yale Interdisciplinary Stress Center that focuses on understanding the neural and psychobiological mechanisms underlying stress, trauma and alcohol and substance use behaviors as well as related conditions such as chronic pain, comfort food intake and obesity that drive increased risk and relapse of chronic medical illnesses. She has developed novel drug craving, stress, pain and food reward provocation paradigms to understand mechanisms that drive these states and related pathologies. Her lab has also developed and tested novel pharmacological and behavioral interventions to address alcohol and substance use behavior change in the context of stress and trauma to decrease addiction relapse risk. She has received a number of awards for her work, including the recent Research Society on Alcoholism鈥檚 Distinguished Researcher Award in 2020, and also the James Tharp Award from the American Society of Addiction Medicine. Her research has been supported by a
series of NIH funded research projects continuously for over 30 years.
She has published over 400 scientific peer reviewed publications with a Google Scholar H-
Index of 122 and her work has been cited over 54,369 times. She has previously served on the US National Institutes of Health鈥檚 (NIH) National Scientific Advisory Council for the National Institute of Drug Abuse (NIDA), the NIH Expert Scientific Panel for the NIH Common Fund鈥檚 Science of Behavior Change program and on NIH Alcohol Institute鈥檚 (/NIAAA) Scientific Advisory Council. She has presented at numerous national and international conferences, and her work is widely cited.
She has been featured as an expert on stress and trauma and its effects on memory, cognition, emotion and health behaviors for numerous news outlets, including the Dr. OZ Show, NBC Nightly News, CNN Health, Wall Street Journal and USA Today and featured in the HBO Documentary entitled 鈥淥ne Nation Under Stress鈥 hosted by Dr. Sanjay Gupta. She conducts workshops, lectures and retreats on stress management, self-care for the stressed professional and for senior executives and other community groups, and on ways to reduce stress to enrich and enhance work, family and personal growth and development.
罢颈迟濒别:听鈥淗ijacking of Stress Coping Circuits And Addiction Risk and Relapse Outcomes鈥
础产蝉迟谤补肠迟:听How is alcohol and drug use linked to stress? Does drug use hijack the ability to face and cope with stress and drive compulsive seeking? This lecture will discuss neural circuits underlying adaptive stress coping and how drug misuse hijacks that to drive higher craving and drug intake and also result in high rates of relapse and treatment failure. The final part of the lecture will present adrenergic and neurosteroid targets that may reverse such stress-related hijacking of adaptive coping to improve treatment outcomes.
Biography:
Rajita Sinha, Ph.D. is the Foundations Fund Endowed Professor of Psychiatry, and Professor in Neuroscience and in Child Psychiatry at the Yale University School of Medicine. She is a
licensed Clinical Psychologist and Clinical Neuroscientist, Chief of the Psychology Section in Psychiatry and Deputy Chair of Psychiatry for Psychology at the Yale University School of
Medicine. She is the founding director of the Yale Interdisciplinary Stress Center that focuses on understanding the neural and psychobiological mechanisms underlying stress, trauma and alcohol and substance use behaviors as well as related conditions such as chronic pain, comfort food intake and obesity that drive increased risk and relapse of chronic medical illnesses. She has developed novel drug craving, stress, pain and food reward provocation paradigms to understand mechanisms that drive these states and related pathologies. Her lab has also developed and tested novel pharmacological and behavioral interventions to address alcohol and substance use behavior change in the context of stress and trauma to decrease addiction relapse risk. She has received a number of awards for her work, including the recent Research Society on Alcoholism鈥檚 Distinguished Researcher Award in 2020, and also the James Tharp Award from the American Society of Addiction Medicine. Her research has been supported by a
series of NIH funded research projects continuously for over 30 years.
She has published over 400 scientific peer reviewed publications with a Google Scholar H-
Index of 122 and her work has been cited over 54,369 times. She has previously served on the US National Institutes of Health鈥檚 (NIH) National Scientific Advisory Council for the National Institute of Drug Abuse (NIDA), the NIH Expert Scientific Panel for the NIH Common Fund鈥檚 Science of Behavior Change program and on NIH Alcohol Institute鈥檚 (/NIAAA) Scientific Advisory Council. She has presented at numerous national and international conferences, and her work is widely cited.
She has been featured as an expert on stress and trauma and its effects on memory, cognition, emotion and health behaviors for numerous news outlets, including the Dr. OZ Show, NBC Nightly News, CNN Health, Wall Street Journal and USA Today and featured in the HBO Documentary entitled 鈥淥ne Nation Under Stress鈥 hosted by Dr. Sanjay Gupta. She conducts workshops, lectures and retreats on stress management, self-care for the stressed professional and for senior executives and other community groups, and on ways to reduce stress to enrich and enhance work, family and personal growth and development.